Noninvasive follicular thyroid neoplasm with papillary nuclear characteristics: Clinicopathologic features and follow-up
Oscar Brunás, José Luis Novelli, Stella Batallés
Abstract
Introduction: A lesion structurally encapsulated or with noninfiltrating expansive edges, follicular pattern growth, 40 mm). All were treated with total thyroidectomy and 20/21 received an ablative dose of I131. At the follow-up (>5 years on average), there were no cases of local, regional or systemic, biochemical or structural recurrences. Comparing the NIFTP and non-NIFTP, similar tumor features were found for the age, gender, maximum tumor dimension, surgical extension, and iodine ablation, median follow-up and recurrent events; p>0.05, without statistical significance. Conclusion: Twenty percent of follicular variant papillary carcinomas now reclassified as NIFTP were overtreated and overcontrolled as if they were PTC; no recurrent events or deaths were detected. We cannot distinguish whether the good prognosis is due to the nature of these neoplasms or to overtreatment.
Keywords
References
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