Desmoplastic melanoma
Guilherme Luiz Furlan, Mateus Bignotto Bortolozzo, Kauê de Carvalho Moura, Sílvia Migueis Picado Petrarolha, Rogério Aparecido Dedivitis
Abstract
Desmoplastic melanoma is a rare variant of malignant melanoma that accounts for 1-5% of all forms of this neoplasm. It usually affects patients in the 6th and 7th decades of life. A 42-year-old female patient with progressive scalp lesion and diagnosis of desmoplastic melanoma is described, presenting good evolution with immunotherapy using Pembrolizumab, avoiding surgical treatment.
Keywords
References
1. Bastos CS Jr, Maceira JMP, Moraes FMB. Desmoplastic melanoma associated with an intraepidermal lentiginous lesion: case report and literature review. An Bras Dermatol. 2013;88(3):408-12. http://dx.doi.org/10.1590/abd1806-4841.20131817. PMid:23793214.
2. Ferreira FR, Ferrari B, Acedo LMS, Ujihara JED, Lira MLA, Mandelbaum SH. Melanoma desmoplásico - um desafio diagnóstico. Surg Cosmet Dermatol. 2015;7(2):184-187.
3. Cabrera R, Recule F. Unusual clinical presentations of malignant melanoma: a review of clinical and histologic features with special emphasis on dermatoscopic findings. Am J Clin Dermatol. 2018;19(Suppl 1):15-23. http://dx.doi.org/10.1007/s40257-018-0373-6. PMid:30374898.
4. Paschoal FM, Yamada VL, Enokihara MMS, Machado Filho CDS. Melanoma desmoplásico. Surg Cosmet Dermatol. 2012;4(1):1-7.
5. Eroglu Z, Zaretsky JM, Hu-Lieskovan S, Kim DW, Algazi A, Johnson DB, Liniker E, Ben Kong, Munhoz R, Rapisuwon S, Gherardini PF, Chmielowski B, Wang X, Shintaku IP, Wei C, Sosman JA, Joseph RW, Postow MA, Carlino MS, Hwu WJ, Scolyer RA, Messina J, Cochran AJ, Long GV, Ribas A. High response rate to PD-1 blockade in desmoplastic melanomas. Nature. 2018;553(7688):347-50. http://dx.doi.org/10.1038/nature25187. PMid:29320474.
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