Granular cell tumor on the larynx
Luna Karla Neves Melo, Eduardo Henrique Silva Chagas, Valmir Tunala Junior, Bruno de Carvalho Dornelas
Granular cell tumors (GCTs) are neoplastic lesions rarely seen in adults. GCTs are most commonly found in the head and neck region, and exceptionally on the larynx. Laryngeal GCTs symptoms and signs may manifest as hoarseness, dysphagia, coughing, hemoptysis, and stridor. We report a case of a 36-year-old woman, who complained of dysphonia. Her clinical history, pathological findings, and treatment are addressed in this article.
1. Hwang I, Hwang JE, Choi SH, Nam SY, Cho KJ. Granular cell tumors of the larynx – report of three cases. Korean J Pathol. 2007;41:284-7.
2. Sobel HJ, Marquet E. Granular cells and granular cell lesions. Pathol Annu. 1974;9(0):43-79. PMid:4371717.
3. Fisher ER, Wechsler H. Granular cell myoblastoma-a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma). Cancer. 1962;15(5):936-54. http://dx.doi.org/10.1002/1097-0142(196209/10)15:5<936::AID-CNCR2820150509>3.0.CO;2-F. PMid:13893237.
4. McIntyre CJ, Allen JL, Powell H, Sandhu G. Novel surgical management of laryngeal granular cell tumour. BMJ Case Rep. 2015;2015. http://dx.doi.org/10.1136/bcr2015-209476. PMid:26150630.
5. Park J-H, Do N-Y, Cho S-II, Choi J-Y. Granular cell tumor on larynx. Clin Exp Otorhinolaryngol. 2010;3(1):52-5. http://dx.doi.org/10.3342/ceo.2010.3.1.52. PMid:20379404.