Spontaneous remission of primary papillary thyroid carcinoma: case report
Gabriela De Martin Silva, Vinicius Antunes Freitas, Flávio Sirihal Werkema, João Batista de Oliveira Andrade, Roger Lanes Silveira
Abstract
Papillary thyroid carcinoma (PTC) is the most common thyroid neoplasm and its spontaneous remission is an extremely exceptional event. In 2010, a 76-year-old male patient was diagnosed in with CPT. Thyroid ultrasonography indicated echographic characteristics of a solid nodule in the distal third of the right lobe, isoechoic, perinodal vascularization, punctate calcification, measuring 10x7.3mm. The cytological report obtained after the Fine Needle Aspiration Biopsy (FNAB) pointed thyroid papillary tumor, indicating total thyroidectomy, surgical proposal refused by the patient. Ten years after the initial diagnosis and clinical follow-up, a cervical Doppler ultrasonography indicated the presence of a solid nodule in the lower third of the right lobe, hypoechoic, regular contours, Chammas II, absent calcification, Ti-RADS 4, measuring 0.7x0.6 cm. In addition, a new cytological report after the FNAB indicated a benign pattern in the sample and spontaneous tumor remission.
Keywords
References
1. Limaiem F, Rehman A, Mazzoni T. Papillary thyroid carcinoma. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 [cited 2021 Aug 17]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536943/
2. Sebastian SO, Gonzalez JM, Paricio PP, Perez JS, Flores DP, Madrona AP, Romero PR, Tebar FJ. Papillary thyroid carcinoma: prognostic index for survival including the histological variety. Arch Surg. 2000;135(3):272-7. http://dx.doi.org/10.1001/archsurg.135.3.272. PMid:10722027.
3. Sipos JA, Haugen BR. Papillary thyroid cancer. In Randolph G, editor. Surgery of the thyroid and parathyroid glands. 3rd ed. Philadelphia: Elsevier; 2021. p. 186-193, 193.e1-193.e5.
4. Shim J, Rao J, Yu R. Spontaneous regression of metastatic papillary thyroid cancer in a lymph node. Case Rep Endocrinol. 2018;2018:5873897. http://dx.doi.org/10.1155/2018/5873897. PMid:29755799.
5. Simpson KW, Albores-Saavedra J. Unusual findings in papillary thyroid microcarcinoma suggesting partial regression: a study of two cases. Ann Diagn Pathol. 2007;11(2):97-102. http://dx.doi.org/10.1016/j.anndiagpath.2006.03.008.PMid:17349567.
6. Marzo-Castillejo M, Vela-Vallespín C. Sobrediagnóstico en cáncer [Overdiagnosis in cancer]. Aten Primaria. 2018;50(Suppl 2):51-6. http://dx.doi.org/10.1016/j.aprim.2018.08.002. PMid:30268494.
7. Dean DS, Gharib H. Fine-needle aspiration biopsy of the thyroid gland. In: Chrousos G, Herder WW, Dhatariya K, Dungan K, Grossman A, Hershman JM, Hofland J, Kalra S, Kaltsas G, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, McGee EA, McLachlan R, Morley JE, New M, Purnell J, Sahay R, Singer F, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000 [cited 2021 Aug 17]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK285544/
Facebook
Google+
Twitter
LinkedIn
Mendeley
StumbleUpon
CiteULike
Reddit
Email